Below-par Arsenal slumped to a 2-0 defeat at Porto although they had already qualified for the last 16.
Arsene Wenger felt confident enough to take a calculated gamble with his team selection.
Wenger: "It will be difficult but we will be up for it and have a chance against anyone in Europe.
Gunners On The Back Foot Before Trip To Boro!
"We were quite comfortable in the first half until the goal tonight.
"What was disappointing was that when we tried to come back we were not capable of being dangerous, we lost balls and then we were on the verge of conceding more."
ARSENAL: Almunia, Eboue, Gallas, Silvestre, Djourou, Ramsey (Wilshere 59), Diaby (Gibbs 59), Song Billong (Randall 78), Denilson, Vela, Bendtner.
Subs Not Used: Fabianski, Hoyte, Merida, Simpson.